Research: Statin intolerance can be overcome
By Brie Zeltner THE PLAIN DEALER
CLEVELAND — Research on a large number of patients who have statin intolerance — those who have failed with two of the cholesterol-lowering medications because of side effects — shows that most of these patients can tolerate the drugs if they are managed carefully.
The Cleveland Clinic findings are important because they affect a lot of people, might help reduce the pain associated with statin side effects, and open a lifesaving treatment for patients who often have complex medical conditions, said Dr. Leslie Cho, section head of preventive cardiology and rehabilitation at the clinic’s Heart & Vascular Institute.
About 25 million Americans take statin drugs (which include familiar brand names such as Lipitor, Crestor, Vytorin and Zocor) every year, but as many as 20 percent of those patients are deemed statin-intolerant. These patients have side effects that include persistent muscle aches in the arms, shoulders, thighs or hips; weakness; gastrointestinal symptoms; and liver problems.
Many times, the soreness is bad enough to make a patient stop taking the medication, Cho said. “That’s a really bad thing, because if you’ve had a heart attack or a stroke, or bypass surgery or something like that, really these medications make you live longer,” Cho said.
Dr. Carl Orringer, a cardiologist at University Hospitals’ Harrington Heart & Vascular Institute in Cleveland, said statin side effects are the No. 1 reason that patients go to the hospital’s lipid clinic.
In the clinic study, 72 percent of the 1,605 patients who had failed with at least two statin medications were able to tolerate the drugs by starting at a lower dose, taking them intermittently or trying a different type of medication in the same class.
Genetics play a role, as do drug interactions. Some medications, such as antibiotics and anti-fungals, increase the time that statins stay in the body and can exacerbate side effects.
Of course, I’ve posted on the “statin thing” and referenced the current prevailing attitude amongst most enlightened doctors that it is rather a hoax. . . . and taking statin drugs do not prevent one from having a heart attack, but rather, sets one up for bringing one on.
The whole idea of cholesterol being so dangerous is much, much overdone. They keep tightening up the guidelines so that ever lower amounts are said to be dangerous when in fact they aren’t. You’ve no doubt heard that they intend to start actively going after the youngsters now to lower their cholesterol thereby gaining much more revenue in that lifetime stream. No matter the side effects. This article loosely refers to the pain which develops in muscles of limbs and liver (3rd paragraph) and so on, but lets face it, the BRAIN and HEART are the most vital muscles our body has. And they are being impacted — big time!
I’m thinking now of two docs in particular with something to say on this, though it is fairly well understood by most. I remember Dr Stephen Sinatra being opposed to the general usage of Statin drugs for the main purpose of the deleterious affect on the body which comes about because it will deplete the Co-Q 10 which the heart so badly needs for function to be normal, or the condition to heal. In extreme and complicated cases only will he use it. Like Dr Sinatra, Dr Russell Blaylock is also a cardiologist with an extensive background. Both of these men have many videos captured on YouTube (discussing many different topics), but I am only referring to heart (cardio) concerns now. I have brought forward a YouTube offering showing Dr Blaylock on Alex Jones’ INFOWARS.com
Radio show host Alex Jones talks with Dr. Russell Blaylock, a retired neurosurgeon and author, about the …